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Rabbit Anti-DLGAP5 Recombinant Antibody (EG968) (CBMAB-EN1150-LY)

The product is antibody recognizes DLGAP5. The antibody EG968 immunoassay techniques such as: WB: 1:500~1:1000 ELISA: 1:40000.
See all DLGAP5 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
EG968
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 ELISA: 1:40000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human DLGAP5.
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
DLG Associated Protein 5
Introduction
DLGAP5 (DLG Associated Protein 5) is a Protein Coding gene. Among its related pathways are Aurora A signaling. Gene Ontology (GO) annotations related to this gene include phosphoprotein phosphatase activity. An important paralog of this gene is DLGAP1.
Entrez Gene ID
9787
UniProt ID
Q15398
Alternative Names
DLG Associated Protein 5; Discs Large Homolog Associated Protein 5; Disks Large-Associated Protein DLG7; Hepatoma Up-Regulated Protein; DAP-5; DLG7; HURP;
Function
Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
Biological Process
Centrosome localization Source: GO_Central
Chromosome segregation Source: GO_Central
Kinetochore assembly Source: GO_Central
Mitotic chromosome movement towards spindle pole Source: UniProtKB
Mitotic spindle organization Source: GO_Central
Positive regulation of mitotic metaphase/anaphase transition Source: UniProtKB
Regulation of mitotic cell cycle Source: GO_Central
Signaling Source: InterPro
Cellular Location
Spindle; Nucleus; Cytoplasm. Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells.
PTM
Ubiquitinated, leading to its degradation.
Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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