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ECSIT

ECSIT (ECSIT Signalling Integrator) is a Protein Coding gene. Diseases associated with ECSIT include Dental Pulp Disease. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Innate Immune System. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and oxidoreductase activity, acting on NAD(P)H.

Full Name

ECSIT homolog (Drosophila)

Research Area

Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity).

Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.

Biological Process

Innate immune response Source: UniProtKB-KW
Regulation of oxidoreductase activity Source: UniProtKB
Regulation of protein complex stability Source: UniProtKB

Cellular Location

Nucleus; Mitochondrion; Cytoplasm

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Anti-ECSIT antibodies

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Mouse Anti-ECSIT Recombinant Antibody (CBFYE-0416) (CBMAB-E0731-FY)

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Target: ECSIT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYE-0416

Application*: E, PLA

Human Recombinant ECSIT protein, His Tag (V2LY-0526-LY3682)

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Target: ECSIT

Expressed Host: E. coli

Sequence: Amino Acid: 246-431

Tag: His Tag

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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