FXR2
The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X cognitive disability syndrome.
Full Name
FMR1 autosomal homolog 2
Function
RNA-binding protein.
Biological Process
Negative regulation of translation Source: GO_Central
Positive regulation of protein phosphorylation Source: GO_Central
Positive regulation of response to DNA damage stimulus Source: GO_Central
Positive regulation of translation Source: GO_Central
Regulation of alternative mRNA splicing, via spliceosome Source: GO_Central
Regulation of filopodium assembly Source: GO_Central
Regulation of mRNA stability Source: GO_Central
Positive regulation of protein phosphorylation Source: GO_Central
Positive regulation of response to DNA damage stimulus Source: GO_Central
Positive regulation of translation Source: GO_Central
Regulation of alternative mRNA splicing, via spliceosome Source: GO_Central
Regulation of filopodium assembly Source: GO_Central
Regulation of mRNA stability Source: GO_Central
Cellular Location
Cytoplasm
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Anti-FXR2 antibodies
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Target: FXR2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A42
Application*: E, IC, IF, IP, WB
Target: FXR2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: EG1248
Application*: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:10000
Target: FXR2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: D85D6
Application*: WB, IF (IC)
Target: FXR2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: CBXF-3247
Application*: WB
Target: FXR2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBXF-0969
Application*: P, WB
Target: FXR2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-0970
Application*: WB
Target: FXR2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBXF-0968
Application*: WB, IP, IF
Target: FXR2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: CBXF-2086
Application*: WB, IF
Target: FXR2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-1981
Application*: WB, IP, IF
Target: FXR2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBXF-3710
Application*: WB, IP, IF, E
Target: FXR2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1G2
Application*: IF, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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