Mouse Anti-FXR2 (C-term) Recombinant Antibody (CBXF-0970) (CBMAB-F2503-CQ)

Name: Mouse Anti-FXR2 (C-term) Recombinant Antibody (CBXF-0970)
SKU: CBMAB-F2503-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXF-0970

Application

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Preservative

0.1% sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

C-term

More Infomation

Target

Full Name

FMR1 autosomal homolog 2

Introduction

The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X cognitive disability syndrome.

Entrez Gene ID

9513

UniProt ID

P51116

Alternative Names

FMR1 Autosomal Homolog 2; Fragile X Mental Retardation, Autosomal Homolog 2; FMR1L2; Fragile X Mental Retardation Syndrome-Related Protein 2; Fragile X-Mental Retardation 1-Like 2; FXR2P;

Function

RNA-binding protein.

Biological Process

Negative regulation of translation Source: GO_Central
Positive regulation of protein phosphorylation Source: GO_Central
Positive regulation of response to DNA damage stimulus Source: GO_Central
Positive regulation of translation Source: GO_Central
Regulation of alternative mRNA splicing, via spliceosome Source: GO_Central
Regulation of filopodium assembly Source: GO_Central
Regulation of mRNA stability Source: GO_Central

Cellular Location

Cytoplasm

Saré, R. M., Figueroa, C., Lemons, A., Loutaev, I., & Beebe Smith, C. (2019). Comparative behavioral phenotypes of fmr1 KO, fxr2 het, and fmr1 KO/fxr2 het mice. Brain sciences, 9(1), 13.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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