GABPB1

This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Full Name
Ga Binding Protein Transcription Factor Beta Subunit 1
Function
Transcription factor capable of interacting with purine rich repeats (GA repeats) (PubMed:8441384, PubMed:10675337, PubMed:8816484).

Acts as a a master regulator of nuclear-encoded mitochondrial genes (By similarity).

(Microbial infection) Necessary for the expression of the Adenovirus E4 gene.
Biological Process
Mitochondrion organization Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: MGI
Cellular Location
Nucleus
PTM
Acetylated by EP300/p300. Deacetylated by SIRT7, promoting heterotetramerization and activity.
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Anti-GABPB1 antibodies

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Mouse Anti-GABPB1 Antibody (V2-4656) (CBMAB-0404-YC)

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Target: GABPB1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: V2-4656
Application*: WB, M
Datasheet SDS

Sheep Anti-GABPB1 Recombinant Antibody (CBYY-1547) (CBMAB-1617-YY)

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Target: GABPB1
Host: Sheep
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-1547
Application*: E, WB, DB, IH
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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