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Mouse Anti-GABPB1 Antibody (V2-4656) (CBMAB-0404-YC)

Provided herein are mouse monoclonal antibodies against Human GABPB1. The antibody clone 1A2 can be used for immunoassay techniques, such as WB and MA.
See all GABPB1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-4656
Antibody Isotype
IgG1
Application
WB, MA

Basic Information

Immunogen
Recombinant protein
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Ga Binding Protein Transcription Factor Beta Subunit 1
Introduction
GABPB1 (GA binding protein transcription factor, beta subunit 1) is the GA-binding protein transcription factor, beta subunit. GABPB1 forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. GABPB1 may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function.
Entrez Gene ID
2553
UniProt ID
Q06547
Alternative Names
E4TF1-47; GABPB; GABPB2
Function
Transcription factor capable of interacting with purine rich repeats (GA repeats) (PubMed:8441384, PubMed:10675337, PubMed:8816484).

Acts as a a master regulator of nuclear-encoded mitochondrial genes (By similarity).

(Microbial infection) Necessary for the expression of the Adenovirus E4 gene.
Biological Process
Mitochondrion organization Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: MGI
Cellular Location
Nucleus
PTM
Acetylated by EP300/p300. Deacetylated by SIRT7, promoting heterotetramerization and activity.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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