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Sheep Anti-GABPB1 Recombinant Antibody (CBYY-1547) (CBMAB-1617-YY)

This product is Sheep antibody that recognizes GABPB1. The antibody CBYY-1547 can be used for immunoassay techniques such as: ELISA, WB, Dot, IHC
See all GABPB1 antibodies

Summary

Host Animal
Sheep
Specificity
Human
Clone
CBYY-1547
Antibody Isotype
IgG2a
Application
ELISA, WB, Dot, IHC

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Ga Binding Protein Transcription Factor Beta Subunit 1
Introduction
This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forMouse a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforMouse have been identified for this gene.
Entrez Gene ID
2553
UniProt ID
Q06547
Alternative Names
GA Binding Protein Transcription Factor Beta Subunit 1; Transcription Factor E4TF1-47; Transcription Factor E4TF1-53; Nuclear Respiratory Factor 2; GABP Subunit Beta-2; GABPB-1; E4TF1B; GABPB2; GABPB; GA Binding Protein Transcription Factor Beta Subunit 1 Transcript Variant Gamma-2; GA Binding Protein Transcription Factor, Beta Subunit 2;
Function
Transcription factor capable of interacting with purine rich repeats (GA repeats) (PubMed:8441384, PubMed:10675337, PubMed:8816484).

Acts as a a master regulator of nuclear-encoded mitochondrial genes (By similarity).

(Microbial infection) Necessary for the expression of the Adenovirus E4 gene.
Biological Process
Mitochondrion organization Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: MGI
Cellular Location
Nucleus
PTM
Acetylated by EP300/p300. Deacetylated by SIRT7, promoting heterotetramerization and activity.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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