GALP

This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction.
Full Name
Galanin Like Peptide
Function
Isoform 1:
Hypothalamic neuropeptide which binds to the G-protein-coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion.

Isoform 2:
Exhibits potent and dose-dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, a physiologic effects which does not appear to be mediated via GALR1 or GALR2. Exhibits antimicrobial activity against Gram-negative bacterias, inducing bacterial membrane blebbing (PubMed:23537644).
Biological Process
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Behavioral response to starvation Source: GO_Central
Defense response to Gram-negative bacterium Source: UniProtKB
Modulation of process of other organism Source: UniProtKB
Neuropeptide signaling pathway Source: UniProtKB-KW
Regulation of appetite Source: Ensembl
Response to insulin Source: Ensembl
Cellular Location
Secreted
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Anti-GALP antibodies

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Mouse Galp ELISA Kit (V2LY-0626-LY5853)

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Target: Galp
Sensitivity: 0.0075 ng/mL
Detection Range: 0.015-3 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Datasheet SDS

Human GALP ELISA Kit (V2LY-0626-LY4210)

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Target: GALP
Sensitivity: 0.022 ng/mL
Detection Range: 0.05-10 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS

Rabbit Anti-GALP Recombinant Antibody (BA0087) (CBMAB-0327CQ)

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Target: GALP
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: BA0087
Application*: WB
Datasheet SDS

Rabbit Anti-GALP Recombinant Antibody (BA0088) (CBMAB-0326CQ)

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Target: GALP
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: BA0088
Application*: WB
Datasheet SDS
More Infomation
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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