HMG20B
HMG20B (High Mobility Group 20B) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and chromatin binding. An important paralog of this gene is HMG20A.
Full Name
High Mobility Group 20B
Function
Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.
Biological Process
Cell cycle Source: UniProtKB-KW
Chromatin organization Source: UniProtKB-KW
Negative regulation of protein sumoylation Source: Ensembl
Positive regulation of neuron differentiation Source: Ensembl
Regulation of gene expression Source: GO_Central
Skeletal muscle cell differentiation Source: Ensembl
Chromatin organization Source: UniProtKB-KW
Negative regulation of protein sumoylation Source: Ensembl
Positive regulation of neuron differentiation Source: Ensembl
Regulation of gene expression Source: GO_Central
Skeletal muscle cell differentiation Source: Ensembl
Cellular Location
Nucleus; Chromosome. Localized to condensed chromosomes in mitosis in conjunction with BRCA2.
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Anti-HMG20B antibodies
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Target: HMG20B
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1F6
Application*: WB, E
Target: HMG20B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1524
Application*: WB: 1:500~1:1000 ELISA: 1:20000
Target: HMG20B
Specificity: Human
Target: HMG20B
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYH-1498
Application*: E, IF, P, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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