Mouse Anti-HMG20B (AA 1-109) Recombinant Antibody (CBFYH-1498) (CBMAB-H2456-FY)

Name: Mouse Anti-HMG20B (AA 1-109) Recombinant Antibody (CBFYH-1498)
SKU: CBMAB-H2456-FY
Rating: 5 (1 reviews)

See all HMG20B antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYH-1498

Application

ELISA, IF, IHC-P, WB

Immunogen

Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Immunogen sequence: MLGAEWSKLQ PTEKQRYLDE AEREKQQYMK ELRAYQQSEA YKMCTEKIQE KKIKKEDSSS GLMNTLLNGH KGGDCDGFST FDVPIFTEEF LDQNKAREAE LRRLRKMNV

Specificity

Human

Antibody Isotype

IgG2a, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 1-109

More Infomation

Target

Full Name

High Mobility Group 20B

Introduction

HMG20B (High Mobility Group 20B) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and chromatin binding. An important paralog of this gene is HMG20A.

Entrez Gene ID

10362

UniProt ID

Q9P0W2

Alternative Names

High Mobility Group 20B; Structural DNA-Binding Protein BRAF35; HMG Domain-Containing Protein HMGX2; HMG Domain-Containing Protein 2; Sox-Like Transcriptional Factor; HMG Box-Containing Protein 20B; HMG Box Domain Containing 2; BRCA2-Associated Factor 35; SMARCE1-Related Protein; SMARCE1r; BRAF35

Function

Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.

Biological Process

Cell cycle Source: UniProtKB-KW
Chromatin organization Source: UniProtKB-KW
Negative regulation of protein sumoylation Source: Ensembl
Positive regulation of neuron differentiation Source: Ensembl
Regulation of gene expression Source: GO_Central
Skeletal muscle cell differentiation Source: Ensembl

Cellular Location

Nucleus; Chromosome. Localized to condensed chromosomes in mitosis in conjunction with BRCA2.

Maiques-Diaz, A., Nicosia, L., Basma, N. J., Romero-Camarero, I., Camera, F., Spencer, G. J., ... & Somervaille, T. C. (2022). HMG20B stabilizes association of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block. Oncogene, 41(44), 4841-4854.

Aldughaim, M. S., Alshehri, M. M., Al-yhya, N., Wadaan, M. A., Al-ghamdi, S., Habibullah, M. M., ... & Khan, M. F. (2022). Prefoldin proteins 2/6, and HMG20B are regulated by HDAC1, HDAC3 and are novel therapeutic and prognostic biomarkers in hepatocellular carcinoma. Journal of King Saud University-Science, 34(2), 101812.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-HMG20B (AA 1-109) Recombinant Antibody (CBFYH-1498)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

HMG20B Matched Antibody Pair (549) (CAT#: APMAB-549LY)

Related Products

HMG20B Matched Antibody Pair (549) (CAT#: APMAB-549LY)

Rabbit Anti-HMG20B Recombinant Antibody (EG1524) (CAT#: CBMAB-EN1823-LY)

Mouse Anti-HMG20B Recombinant Antibody (1F6) (CAT#: CBMAB-A3955-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry