Sign in or Register

HOPX

HOP Homeobox is a homeodomain protein that lacks certain conserved residues required for DNA binding. Studies in mice suggest that HOP Homeobox may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development.
Full Name
HOPX
Function
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity).

May act as a tumor suppressor. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding (PubMed:27708256).
Biological Process
Bundle of His development Source: BHF-UCL
Chaperone-mediated protein complex assembly Source: CAFA
Histone deacetylation Source: Ensembl
Lung alveolus development Source: Ensembl
Negative regulation of cell differentiation Source: MGI
Negative regulation of transcription by RNA polymerase II Source: Ensembl
Positive regulation of skeletal muscle tissue regeneration Source: Ensembl
Positive regulation of striated muscle cell differentiation Source: Ensembl
Regulation of heart contraction Source: Ensembl
Regulation of protein binding Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Trophectodermal cell differentiation Source: MGI
Cellular Location
Nucleus; Cytoplasm
View more

Anti-HOPX antibodies

+ Filters
Loading...

Mouse Anti-HOPX Recombinant Antibody (3D6) (CBMAB-A4005-LY)

Go to compareCompare
Target: HOPX
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3D6
Application*: WB, E
Datasheet SDS

Rabbit Anti-HOPX Recombinant Antibody (D6E3) (CBMAB-CP1058-LY)

Go to compareCompare
Target: HOPX
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey, Hamster, Cattle
Clone: D6E3
Application*: WB
Datasheet SDS

Rabbit Anti-HOPX Recombinant Antibody (D10E2) (CBMAB-CP1057-LY)

Go to compareCompare
Target: HOPX
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey, Cattle
Clone: D10E2
Application*: WB, IF (IC), F
Datasheet SDS

Mouse Anti-HOPX (AA 1-74) Recombinant Antibody (CBFYH-1714) (CBMAB-H2719-FY)

Go to compareCompare
Target: HOPX
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-1714
Application*: E, WB
Datasheet SDS

Mouse Anti-HOPX Recombinant Antibody (DS14F5) (CBMAB-H2715-FY)

Go to compareCompare
Target: HOPX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Pig, Cattle, Dog, Chicken, Guinea pig, Hamster, Rabbit, Sheep, Frog
Clone: DS14F5
Application*: WB, IH, IP, P
Datasheet SDS

Mouse Anti-HOPX Recombinant Antibody (CBFYH-1711) (CBMAB-H0713-FY)

Go to compareCompare
Target: HOPX
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-1711
Application*: E, WB
Datasheet SDS

Mouse Anti-HOPX Antibody (1A1) (CBMAB-0496-YC)

Go to compareCompare
Target: HOPX
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1A1
Application*: IP, WB, M
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry