HOXC6
This gene belongs to the homeobox family, members of which encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC6, is one of several HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Alternatively spliced transcript variants encoding different isoforms have been identified for HOXC6. Transcript variant two includes the shared exon, and transcript variant one includes only gene-specific exons.
                Full Name
                    homeobox C6
                Function
                    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
                Biological Process
                    Anterior/posterior pattern specification Source: GO_Central
Embryonic skeletal system development Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
                Embryonic skeletal system development Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
                    Nucleus
                
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                    Anti-HOXC6 antibodies
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        Target: HOXC6
                
                Host: Mouse
                
                Antibody Isotype: IgG2b, κ
                
                Specificity: Human
                
                Clone: 2A4
                
                Application*: WB, E
                
            Target: HOXC6
                
                Host: Rabbit
                
                Antibody Isotype: IgG
                
                Specificity: Human, Mouse
                
                Clone: EG1547
                
                Application*: WB: 1:500~1:1000 ELISA: 1:10000
                
            Target: HOXC6
                
                Host: Mouse
                
                Antibody Isotype: IgG2b, κ
                
                Specificity: Human
                
                Clone: CBFYH-1820
                
                Application*: E, WB
                
            More Infomation
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For Research Use Only. Not For Clinical Use.
                    (P): Predicted
* Abbreviations 
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
 
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