HOXD11
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis. [provided by RefSeq]
                Full Name
                    homeobox D11
                Function
                    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
                Biological Process
                    Anatomical structure development Source: GO_Central
Branching involved in ureteric bud morphogenesis Source: UniProtKB
Dorsal/ventral pattern formation Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
                Branching involved in ureteric bud morphogenesis Source: UniProtKB
Dorsal/ventral pattern formation Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
                    Nucleus
                
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                    Anti-HOXD11 antibodies
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        Target: HOXD11
                
                Host: Mouse
                
                Antibody Isotype: IgG2a, κ
                
                Specificity: Human
                
                Clone: 5E7
                
                Application*: WB, E
                
            Target: HOXD11
                
                Host: Mouse
                
                Antibody Isotype: IgG2a
                
                Specificity: Human
                
                Clone: CBFYH-1842
                
                Application*: WB, IF
                
            Target: HOXD11
                
                Host: Mouse
                
                Antibody Isotype: IgG2a
                
                Specificity: Human
                
                Clone: CBFYH-1841
                
                Application*: WB, E, CI, IF
                
            Target: HOXD11
                
                Host: Mouse
                
                Antibody Isotype: IgG2a, κ
                
                Specificity: Human
                
                Clone: CBFYH-1840
                
                Application*: E, IF, WB
                
            Target: HOXD11
                
                Host: Mouse
                
                Antibody Isotype: IgG2a, κ
                
                Specificity: Human
                
                Clone: CBFYH-1838
                
                Application*: SE, E, WB
                
            Target: HOXD11
                
                Host: Mouse
                
                Antibody Isotype: IgG2a
                
                Specificity: Human
                
                Clone: CBFYH-1839
                
                Application*: E, IC, WB
                
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For Research Use Only. Not For Clinical Use.
                    (P): Predicted
* Abbreviations 
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
 
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