IFNA1
The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011]
Full Name
Interferon Alpha 1
Function
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Biological Process
Adaptive immune response Source: GO_Central
B cell differentiation Source: GO_Central
B cell proliferation Source: GO_Central
Cytokine-mediated signaling pathway Source: GO_Central
Defense response to virus Source: UniProtKB-KW
Humoral immune response Source: GO_Central
Natural killer cell activation involved in immune response Source: GO_Central
Positive regulation of peptidyl-serine phosphorylation of STAT protein Source: GO_Central
Response to exogenous dsRNA Source: GO_Central
T cell activation involved in immune response Source: GO_Central
B cell differentiation Source: GO_Central
B cell proliferation Source: GO_Central
Cytokine-mediated signaling pathway Source: GO_Central
Defense response to virus Source: UniProtKB-KW
Humoral immune response Source: GO_Central
Natural killer cell activation involved in immune response Source: GO_Central
Positive regulation of peptidyl-serine phosphorylation of STAT protein Source: GO_Central
Response to exogenous dsRNA Source: GO_Central
T cell activation involved in immune response Source: GO_Central
Cellular Location
Secreted
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Anti-IFNA1 antibodies
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CompareTarget: IFNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 8C21
Application*: WB
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3C6
Application*: WB, E
Target: IFNA1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBFYA-0002
Application*: F, FN, IA, WB
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: ST47
Application*: E, WB
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: ST225
Application*: FN
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: ST126
Application*: FN
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1868
Application*: E, WB
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Pig
Clone: CBYY-I1832
Application*: N
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-I1718
Application*: E, FN
Target: IFNA1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYY-I1422
Application*: WB
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1175
Application*: E
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1154
Application*: WB
Target: IFNA1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYY-I1139
Application*: E, F, N, WB
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1009
Application*: E, N
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: AE3
Application*: E, WB
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AB5
Application*: E, WB
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 7N41
Application*: E, IH, WB
Target: IFNA1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: 4E-A1
Application*: N
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYY-I0563
Application*: E
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: C10F5
Application*: WB, E, AP, C
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0469
Application*: N, SE
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2.52
Application*: IF, F, E, WB
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-I0096
Application*: F, E, IF
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-I0095
Application*: E, WB
Target: IFNA1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0094
Application*: E, C, WB
Target: Ifna1
Sensitivity: 0.00057 ng/mL
Detection Range: 0.001-0.4 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: IFNA1
Expressed Host: Yeast
Sequence: Amino Acid: 24-189
Tag: His Tag
Target: IFNA1
Expressed Host: Yeast
Sequence: Amino Acid: 24-189
Tag: His Tag
Target: IFNA1
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-192
Tag: His Tag
Target: IFNA1
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-192
Tag: hFc Tag
Target: IFNA1
Specificity: Human
Target: IFNA1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBHb001
Application*: FC, FuncS, Immuno assays, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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