IL13RA2
The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008]
Full Name
Interleukin 13 Receptor Subunit Alpha 2
Function
Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4).
Biological Process
Cytokine-mediated signaling pathway Source: GO_Central
Immunoglobulin mediated immune response Source: Ensembl
Negative regulation of immunoglobulin production Source: Ensembl
Negative regulation of mast cell degranulation Source: Ensembl
Immunoglobulin mediated immune response Source: Ensembl
Negative regulation of immunoglobulin production Source: Ensembl
Negative regulation of mast cell degranulation Source: Ensembl
Cellular Location
Membrane
Topology
Extracellular: 27-343
Helical: 344-363
Cytoplasmic: 364-380
Helical: 344-363
Cytoplasmic: 364-380
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Anti-IL13RA2 antibodies
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CompareTarget: IL13RA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1817
Application*: F, IH, E, FN
Target: IL13RA2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C0242
Application*: F, B, E, IH
Target: IL13RA2
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 8F16
Application*: WB
Target: IL13RA2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-336
Tag: His Tag
Target: IL13RA2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-336
Tag: hFc Tag
Target: IL13RA2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-334
Tag: His Tag
Target: IL13RA2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-334
Tag: His & hFc Tag
Target: IL13RA2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-334
Tag: Fc Tag
Target: IL13RA2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-334
Tag: hFc Tag
Target: IL13RA2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-342
Tag: His Tag
Target: IL13RA2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-342
Tag: His & hFc Tag
Target: IL13RA2
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 27-342
Tag: His & AVI Tag
Target: IL13RA2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-342
Tag: His Tag
Target: IL13RA2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-342
Tag: His Tag
Target: IL13RA2
Expressed Host: CHO cells
Sequence: Amino Acid: 1-343
Tag: hFc Tag
Target: IL13RA2
Expressed Host: CHO Cells
Sequence: Amino Acid: 1-343
Tag: hFc & AVI Tag
Target: IL13RA2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-338
Tag: His Tag
Target: IL13RA2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-338
Tag: hFc Tag
Target: IL13RA2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1632
Application*: WB: 1:500~1:1000 ELISA: 1:20000
Target: IL13RA2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: E7U7B
Application*: WB, IP, F
Target: IL13RA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B-D13
Application*: E, P, F, FN
Target: IL13RA2
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0799
Application*: F
Target: IL13RA2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-I1578
Application*: E
Target: IL13RA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1398
Application*: E, F
Target: IL13RA2
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYY-I1339
Application*: WB
Target: IL13RA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1183
Application*: F
Target: IL13RA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0854
Application*: F, P, C
Target: IL13RA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0772
Application*: WB
Target: IL13RA2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0771
Application*: EC
Target: IL13RA2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2E10
Application*: E, RNAi, WB
Target: IL13RA2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 47
Application*: F
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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