INA

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons.
Full Name
internexin neuronal intermediate filament protein alpha
Function
Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges. May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks (By similarity).
Biological Process
Cell differentiationIEA:UniProtKB-KW
Cellular response to leukemia inhibitory factorIEA:Ensembl
Neurofilament cytoskeleton organizationIEA:Ensembl
Substantia nigra developmentManual Assertion Based On ExperimentHEP:UniProtKB
Cellular Location
Cytoplasmic ribonucleoprotein granule; Extracellular space; Neurofilament; Postsynapse; Schaffer collateral - CA1 synapse
PTM
O-glycosylated.
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Anti-INA antibodies

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Target: INA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG1653
Application*: WB: 1:500~1:1000 ELISA: 1:40000
Target: INA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: 9i172
Application*: F, IC, IH, IP, WB
Target: INA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0245
Application*: IF, P, WB
Target: INA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: 257CT7.1.2
Application*: WB, P, IF, E, IC, IH
Target: INA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-A986
Application*: WB, IH
Target: INA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: NF66
Application*: WB, IH, IC, IF, P, IF
Target: INA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Cattle, Mouse, Frog
Clone: ID2
Application*: E, IF, WB, IH
Target: INA
Host: Mouse
Antibody Isotype: IgG, κ
Specificity: Mouse
Clone: 7.1.2
Application*: WB, IC, IF, P
Target: INA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: 2E4
Application*: WB, IH, IC, IF, P, C
Target: INA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 2E3
Application*: E, F, IC, IF, IH, WB
Target: INA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EP676Y
Application*: F, IF, P, IP, WB
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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