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INA

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons.
Full Name
internexin neuronal intermediate filament protein alpha
Function
Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges. May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks (By similarity).
Biological Process
Cell differentiationIEA:UniProtKB-KW
Cellular response to leukemia inhibitory factorIEA:Ensembl
Neurofilament cytoskeleton organizationIEA:Ensembl
Substantia nigra developmentManual Assertion Based On ExperimentHEP:UniProtKB
Cellular Location
Cytoplasmic ribonucleoprotein granule; Extracellular space; Neurofilament; Postsynapse; Schaffer collateral - CA1 synapse
PTM
O-glycosylated.

Anti-INA antibodies

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Target: INA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: 9i172
Application*: F, IC, IH, IP, WB
Target: INA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0245
Application*: IF, P, WB
Target: INA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: 257CT7.1.2
Application*: WB, P, IF, E, IC, IH
Target: INA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EG1653
Application*: WB: 1:500~1:1000 ELISA: 1:40000
Target: INA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-A986
Application*: WB, IH
Target: INA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: NF66
Application*: WB, IH, IC, IF, P, IF
Target: INA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Cattle, Mouse, Frog
Clone: ID2
Application*: E, IF, WB, IH
Target: INA
Host: Mouse
Antibody Isotype: IgG, κ
Specificity: Mouse
Clone: 7.1.2
Application*: WB, IC, IF, P
Target: INA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: 2E4
Application*: WB, IH, IC, IF, P, C
Target: INA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 2E3
Application*: E, F, IC, IF, IH, WB
Target: INA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EP676Y
Application*: F, IF, P, IP, WB
Target: INA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EPR1529
Application*: WB, P, IC
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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