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Mouse Anti-INA Recombinant Antibody (ID2) (CBMAB-A4488-YC)

Provided herein is a Mouse monoclonal antibody against Human Internexin Neuronal Intermediate Filament Protein Alpha. The antibody can be used for immunoassay techniques, such as ELISA, IF, WB, IHC.
See all INA antibodies

Summary

Host Animal
Mouse
Specificity
Human, Cattle, Mouse, Frog
Clone
ID2
Antibody Isotype
IgG1
Application
ELISA, IF, WB, IHC

Basic Information

Immunogen
Recombinant rat alpha-internexin expressed in E. coli
Specificity
Human, Cattle, Mouse, Frog
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.4, 0.09% sodium azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
internexin neuronal intermediate filament protein alpha
Introduction
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport
Entrez Gene ID
Human9118
Mouse226180
Cattle532236
Frog100101732
UniProt ID
HumanQ16352
MouseP46660
CattleQ08DH7
FrogF7DRR7
Alternative Names
Internexin Neuronal Intermediate Filament Protein Alpha
Function
Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges. May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks (By similarity).
Biological Process
Cell differentiationIEA:UniProtKB-KW
Cellular response to leukemia inhibitory factorIEA:Ensembl
Neurofilament cytoskeleton organizationIEA:Ensembl
Substantia nigra developmentManual Assertion Based On ExperimentHEP:UniProtKB
Cellular Location
Cytoplasmic ribonucleoprotein granule; Extracellular space; Neurofilament; Postsynapse; Schaffer collateral - CA1 synapse
PTM
O-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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