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Rabbit Anti-INA Recombinant Antibody (EP676Y) (CBMAB-1587-CN)

This product is a rabbit antibody that recognizes INA of human. The antibody EP676Y can be used for immunoassay techniques such as: FC, IF, IHC-P, IP, WB.
See all INA antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EP676Y
Antibody Isotype
IgG
Application
FC, IF, IHC-P, IP, WB

Basic Information

Immunogen
Synthetic peptide corresponding to residues in the tail domain (Human)
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
49% PBS, 0.05% BSA, 50% Glycerol
Preservative
0.01% Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
internexin neuronal intermediate filament protein alpha
Introduction
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.
Entrez Gene ID
Human9118
Mouse226180
Rat24503
UniProt ID
HumanQ16352
MouseP46660
RatP23565
Alternative Names
NEF5; NF-66; TXBP-1
Function
Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges. May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks (By similarity).
Biological Process
Cell differentiationIEA:UniProtKB-KW
Cellular response to leukemia inhibitory factorIEA:Ensembl
Neurofilament cytoskeleton organizationIEA:Ensembl
Substantia nigra developmentManual Assertion Based On ExperimentHEP:UniProtKB
Cellular Location
Cytoplasmic ribonucleoprotein granule; Extracellular space; Neurofilament; Postsynapse; Schaffer collateral - CA1 synapse
PTM
O-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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