ITGB5

This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin. [provided by RefSeq, Aug 2017]
Full Name
Integrin Subunit Beta 5
Function
Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
(Microbial infection) Integrin ITGAV:ITGB5 acts as a receptor for adenovirus type C.
Biological Process
Cell adhesion mediated by integrinManual Assertion Based On ExperimentIBA:GO_Central
Cell migrationManual Assertion Based On ExperimentIMP:BHF-UCL
Cell-matrix adhesionManual Assertion Based On ExperimentIMP:UniProtKB
Endodermal cell differentiationManual Assertion Based On ExperimentIEP:UniProtKB
Epithelial cell-cell adhesionManual Assertion Based On ExperimentIMP:UniProtKB
Integrin-mediated signaling pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Stress fiber assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Transforming growth factor beta receptor signaling pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 24-719
Helical: 720-742
Cytoplasmic: 743-799
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Anti-ITGB5 antibodies

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Mouse Anti-ITGB5 Recombinant Antibody (1D8) (CBMAB-A4588-LY)

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Target: ITGB5
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1D8
Application*: WB, E
Datasheet SDS

Mouse Anti-ITGB5 (AA 30-206) Recombinant Antibody (CBYY-I0841) (CBMAB-I1920-YY)

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Target: ITGB5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-I0841
Application*: F
Datasheet SDS

Rabbit Anti-ITGB5 Recombinant Antibody (CBYY-I0548) (CBMAB-I1232-YY)

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Target: ITGB5
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: CBYY-I0548
Application*: WB, IP, IF
Datasheet SDS

Mouse Anti-ITGB5 Recombinant Antibody (CBYY-I0388) (CBMAB-I0975-YY)

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Target: ITGB5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0388
Application*: E, F, IF, C, IP, FN, IC, P
Datasheet SDS

Mouse Anti-ITGB5 Recombinant Antibody (CBYY-I0387) (CBMAB-I0974-YY)

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Target: ITGB5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Chicken
Clone: CBYY-I0387
Application*: C, E, F, IF, IP
Datasheet SDS

Mouse Anti-ITGB5 Recombinant Antibody (CBYY-I0283) (CBMAB-I0793-YY)

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Target: ITGB5
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Hamster, Human, Mouse
Clone: CBYY-I0283
Application*: FC, WB, Block, ICC
Datasheet SDS

Mouse Anti-ITGB5 Recombinant Antibody (CBT4566) (V2LY-0625-LY1864)

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Target: ITGB5
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT4566
Application*: IC, F
Datasheet SDS

Mouse Anti-ITGB5 Recombinant Antibody (CBT2655) (V2LY-0625-LY1721)

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Target: ITGB5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2655
Application*: F
Datasheet SDS

ITGB5 Matched Antibody Pair (652) (APMAB-652LY)

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Target: ITGB5
Specificity: Human
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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