ITGB5
This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin. [provided by RefSeq, Aug 2017]
Full Name
Integrin Subunit Beta 5
Function
Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
(Microbial infection) Integrin ITGAV:ITGB5 acts as a receptor for adenovirus type C.
(Microbial infection) Integrin ITGAV:ITGB5 acts as a receptor for adenovirus type C.
Biological Process
Cell adhesion mediated by integrinManual Assertion Based On ExperimentIBA:GO_Central
Cell migrationManual Assertion Based On ExperimentIMP:BHF-UCL
Cell-matrix adhesionManual Assertion Based On ExperimentIMP:UniProtKB
Endodermal cell differentiationManual Assertion Based On ExperimentIEP:UniProtKB
Epithelial cell-cell adhesionManual Assertion Based On ExperimentIMP:UniProtKB
Integrin-mediated signaling pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Stress fiber assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Transforming growth factor beta receptor signaling pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Cell migrationManual Assertion Based On ExperimentIMP:BHF-UCL
Cell-matrix adhesionManual Assertion Based On ExperimentIMP:UniProtKB
Endodermal cell differentiationManual Assertion Based On ExperimentIEP:UniProtKB
Epithelial cell-cell adhesionManual Assertion Based On ExperimentIMP:UniProtKB
Integrin-mediated signaling pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Stress fiber assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Transforming growth factor beta receptor signaling pathwayManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 24-719
Helical: 720-742
Cytoplasmic: 743-799
Helical: 720-742
Cytoplasmic: 743-799
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Anti-ITGB5 antibodies
Products List
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CompareTarget: ITGB5
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1D8
Application*: WB, E
Target: ITGB5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-I0841
Application*: F
Target: ITGB5
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: CBYY-I0548
Application*: WB, IP, IF
Target: ITGB5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0388
Application*: E, F, IF, C, IP, FN, IC, P
Target: ITGB5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Chicken
Clone: CBYY-I0387
Application*: C, E, F, IF, IP
Target: ITGB5
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Hamster, Human, Mouse
Clone: CBYY-I0283
Application*: FC, WB, Block, ICC
Target: ITGB5
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT4566
Application*: IC, F
Target: ITGB5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2655
Application*: F
Target: ITGB5
Specificity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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