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KDM3B

Histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.

Full Name

Lysine Demethylase 3B

Function

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.

Biological Process

Chromatin organizationIEA:UniProtKB-KW
Histone H3-K9 demethylationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

Involvement in disease

Diets-Jongmans syndrome (DIJOS):
An autosomal dominant disorder characterized by varying degrees of intellectual disability, developmental delay, short stature, and characteristic facial features such as a wide mouth, a pointed chin, long ears and a low columella.

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Anti-KDM3B antibodies

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Mouse Anti-KDM3B Recombinant Antibody (CBLXK-003) (CBMAB-2208CQ)

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Target: KDM3B

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Mouse, Rat

Clone: CBLXK-003

Application*: WB, IP, IC, IH, F

Rabbit Anti-KDM3B Recombinant Antibody (S.393.0) (CBMAB-0446-WJ)

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Target: KDM3B

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: S.393.0

Application*: IC, IF, IP, WB

Rabbit Anti-KDM3B Recombinant Antibody (C6D12) (CBMAB-0304-WJ)

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Target: KDM3B

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Monkey

Clone: C6D12

Application*: WB, IP, P

Rabbit Anti-KDM3B Recombinant Antibody (C69G2) (CBMAB-0303-WJ)

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Target: KDM3B

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Monkey

Clone: C69G2

Application*: WB, IP, IF

Mouse Anti-KDM3B Recombinant Antibody (CBLXK-004) (CBMAB-2209CQ)

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Target: KDM3B

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat, Monkey

Clone: CBLXK-004

Application*: WB, IP, IF

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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