KDM3B

Histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
Full Name
Lysine Demethylase 3B
Function
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
Biological Process
Chromatin organizationIEA:UniProtKB-KW
Histone H3-K9 demethylationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
Involvement in disease
Diets-Jongmans syndrome (DIJOS):
An autosomal dominant disorder characterized by varying degrees of intellectual disability, developmental delay, short stature, and characteristic facial features such as a wide mouth, a pointed chin, long ears and a low columella.
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Anti-KDM3B antibodies

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Mouse Anti-KDM3B Recombinant Antibody (CBLXK-003) (CBMAB-2208CQ)

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Target: KDM3B
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: CBLXK-003
Application*: WB, IP, IC, IH, F
Datasheet SDS

Rabbit Anti-KDM3B Recombinant Antibody (S.393.0) (CBMAB-0446-WJ)

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Target: KDM3B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: S.393.0
Application*: IC, IF, IP, WB
Datasheet SDS

Rabbit Anti-KDM3B Recombinant Antibody (C6D12) (CBMAB-0304-WJ)

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Target: KDM3B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: C6D12
Application*: WB, IP, P
Datasheet SDS

Rabbit Anti-KDM3B Recombinant Antibody (C69G2) (CBMAB-0303-WJ)

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Target: KDM3B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: C69G2
Application*: WB, IP, IF
Datasheet SDS

Mouse Anti-KDM3B Recombinant Antibody (CBLXK-004) (CBMAB-2209CQ)

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Target: KDM3B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Monkey
Clone: CBLXK-004
Application*: WB, IP, IF
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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