KDM3B

Histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.

Full Name

Lysine Demethylase 3B

Function

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.

Biological Process

Chromatin organizationIEA:UniProtKB-KW
Histone H3-K9 demethylationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

Involvement in disease

Diets-Jongmans syndrome (DIJOS):
An autosomal dominant disorder characterized by varying degrees of intellectual disability, developmental delay, short stature, and characteristic facial features such as a wide mouth, a pointed chin, long ears and a low columella.

Anti-KDM3B antibodies

Rabbit Anti-KDM3B Recombinant Antibody (S.393.0) (CBMAB-0446-WJ)

Datasheet

SDS

Target: KDM3B

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: S.393.0

Application*: IC, IF, IP, WB

Rabbit Anti-KDM3B Recombinant Antibody (C6D12) (CBMAB-0304-WJ)

Datasheet

SDS

Target: KDM3B

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Monkey

Clone: C6D12

Application*: WB, IP, P

Rabbit Anti-KDM3B Recombinant Antibody (C69G2) (CBMAB-0303-WJ)

Datasheet

SDS

Target: KDM3B

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Monkey

Clone: C69G2

Application*: WB, IP, IF

Mouse Anti-KDM3B Recombinant Antibody (CBLXK-004) (CBMAB-2209CQ)

Datasheet

SDS

Target: KDM3B

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat, Monkey

Clone: CBLXK-004

Application*: WB, IP, IF

Mouse Anti-KDM3B Recombinant Antibody (CBLXK-003) (CBMAB-2208CQ)

Datasheet

SDS

Target: KDM3B

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Mouse, Rat

Clone: CBLXK-003

Application*: WB, IP, IC, IH, F

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)