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LCOR

LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor box.

Full Name

LCOR

Function

May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3' (By similarity).
Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR.

Biological Process

Cellular response to estradiol stimulusManual Assertion Based On ExperimentIDA:ARUK-UCL
Negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:ARUK-UCL
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

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Anti-LCOR antibodies

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Mouse Anti-LCOR Recombinant Antibody (CBYJL-1310) (CBMAB-L0891-YJ)

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Target: LCOR

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJL-1310

Application*: WB, IP, IF, E

Mouse Anti-LCOR Recombinant Antibody (CBYJL-1308) (CBMAB-L0889-YJ)

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Target: LCOR

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBYJL-1308

Application*: WB, IP, IF, E

Mouse Anti-LCOR Recombinant Antibody (CBYJL-1307) (CBMAB-L0888-YJ)

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Target: LCOR

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJL-1307

Application*: IC, IF

Mouse Anti-LCOR Recombinant Antibody (CBYJL-1305) (CBMAB-L0886-YJ)

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Target: LCOR

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJL-1305

Application*: WB

Mouse Anti-LCOR Recombinant Antibody (CBYJL-1303) (CBMAB-L0884-YJ)

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Target: LCOR

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJL-1303

Application*: WB

Mouse Anti-LCOR (AA 204-433) Recombinant Antibody (CBFYM-1209) (CBMAB-M1366-FY)

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Target: LCOR

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBFYM-1209

Application*: WB

Mouse Anti-LCOR Antibody (1A7) (CBMAB-0608-YC)

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Target: LCOR

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 1A7

Application*: IP, M

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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