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LCOR

LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor box.
Full Name
LCOR
Function
May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3' (By similarity).
Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR.
Biological Process
Cellular response to estradiol stimulusManual Assertion Based On ExperimentIDA:ARUK-UCL
Negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:ARUK-UCL
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus

Anti-LCOR antibodies

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Mouse Anti-LCOR Antibody (1A7) (CBMAB-0608-YC)

Datasheet SDS
Target: LCOR
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1A7
Application*: IP, M

Mouse Anti-LCOR Recombinant Antibody (CBYJL-1303) (CBMAB-L0884-YJ)

Datasheet SDS
Target: LCOR
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-1303
Application*: WB

Mouse Anti-LCOR Recombinant Antibody (CBYJL-1305) (CBMAB-L0886-YJ)

Datasheet SDS
Target: LCOR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1305
Application*: WB

Mouse Anti-LCOR Recombinant Antibody (CBYJL-1307) (CBMAB-L0888-YJ)

Datasheet SDS
Target: LCOR
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-1307
Application*: IC, IF

Mouse Anti-LCOR Recombinant Antibody (CBYJL-1308) (CBMAB-L0889-YJ)

Datasheet SDS
Target: LCOR
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBYJL-1308
Application*: WB, IP, IF, E

Mouse Anti-LCOR Recombinant Antibody (CBYJL-1310) (CBMAB-L0891-YJ)

Datasheet SDS
Target: LCOR
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1310
Application*: WB, IP, IF, E

Mouse Anti-LCOR (AA 204-433) Recombinant Antibody (CBFYM-1209) (CBMAB-M1366-FY)

Datasheet SDS
Target: LCOR
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYM-1209
Application*: WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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