LDHB
LDHB is the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency.
Full Name
LDHB
Biological Process
Carbohydrate metabolic processIEA:InterPro
Lactate metabolic processManual Assertion Based On ExperimentIDA:ComplexPortal
Pyruvate metabolic processManual Assertion Based On ExperimentIDA:ComplexPortal
Lactate metabolic processManual Assertion Based On ExperimentIDA:ComplexPortal
Pyruvate metabolic processManual Assertion Based On ExperimentIDA:ComplexPortal
Cellular Location
Cytoplasm
Mitochondrion inner membrane
Mitochondrion inner membrane
Involvement in disease
Lactate dehydrogenase B deficiency (LDHBD):
A condition with no deleterious effects on health. LDHBD is of interest to laboratory medicine mainly because it can cause misdiagnosis in those disorders in which elevation of serum LDH is expected.
A condition with no deleterious effects on health. LDHBD is of interest to laboratory medicine mainly because it can cause misdiagnosis in those disorders in which elevation of serum LDH is expected.
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Anti-LDHB antibodies
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CompareTarget: LDHB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2H6
Application*: WB, E
Target: LDHB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYCL-198
Application*: E, WB
Target: LDHB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYCL-197
Application*: E, IF, P, WB
Target: LDHB
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBYCL-196
Application*: E, IC, WB
Target: LDHB
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYCL-195
Application*: E, IC, WB
Target: LDHB
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBYCL-194
Application*: WB, IC, P, C, E
Target: LDHB
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYCL-193
Application*: WB, IC, P, C, E
Target: LDHB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYCL-192
Application*: E, WB, P, IF, IC
Target: LDHB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EP1566Y
Application*: IC, IF
Target: LDHB
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1361
Application*: WB, IC, P, E
Target: LDHB
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: AT14D7
Application*: E, WB
Target: LDHB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: AF60H11
Application*: WB, P, IF, IP
Target: LDHB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: AF21F4
Application*: WB, E
Target: LDHB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CBYJL-1360
Application*: WB, IP, E, P, F, IC, IF
Target: LDHB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJL-1358
Application*: IF, WB
Target: LDHB
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1357
Application*: E, WB
Target: LDHB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 2057D
Application*: IS
Target: LDHB
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-1356
Application*: WB, F, E, IC, IF
Target: LDHB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1355
Application*: IP, F, IC, IF, E
Target: LDHB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-1354
Application*: WB, E
Target: LDHB
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: A885
Application*: ICC, IHC, IP, WB
Target: LDHB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: A884
Application*: ELISA, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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