LHX5
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in the control of differentiation and development of the forebrain. In mice, this protein is essential for the regulation of precursor cell proliferation and the control of neuronal differentiation and migration during hippocampal development. This protein is involved in learning and motor functions in adult mice. [provided by RefSeq]
Full Name
LIM homeobox 5
Function
Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system.
Biological Process
Cell proliferation in forebrainIEA:Ensembl
Cerebellar Purkinje cell differentiationIEA:Ensembl
Cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferationIEA:Ensembl
Forebrain neuron differentiationIEA:Ensembl
Hippocampus developmentIEA:Ensembl
Neuron differentiationManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of transcription, DNA-templatedIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Spinal cord association neuron differentiationIEA:Ensembl
Cerebellar Purkinje cell differentiationIEA:Ensembl
Cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferationIEA:Ensembl
Forebrain neuron differentiationIEA:Ensembl
Hippocampus developmentIEA:Ensembl
Neuron differentiationManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of transcription, DNA-templatedIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Spinal cord association neuron differentiationIEA:Ensembl
Cellular Location
Nucleus
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Anti-LHX5 antibodies
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Target: LHX5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2B4
Application*: E, E
Target: LHX5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2B11
Application*: WB, E
Target: LHX5
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2A8
Application*: IF, E
Target: LHX5
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYCL-302
Application*: E, IC, WB
Target: LHX5
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYCL-301
Application*: WB, E, IC, IF
Target: LHX5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-1631
Application*: E, WB
Target: LHX5
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1630
Application*: E
Target: LHX5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-1629
Application*: E, IF, WB
Target: LHX5
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJL-1628
Application*: E, IF
Target: LHX5
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1627
Application*: E, WB
Target: LHX5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1B7
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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