LMAN2
This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus and the plasma membrane.
Full Name
LECTIN, MANNOSE BINDING 2
Function
Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans (By similarity).
Biological Process
Endoplasmic reticulum organizationManual Assertion Based On ExperimentIBA:GO_Central
Endoplasmic reticulum to Golgi vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Golgi organizationManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of phagocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Protein transportIEA:UniProtKB-KW
Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulumManual Assertion Based On ExperimentIMP:UniProtKB
Endoplasmic reticulum to Golgi vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Golgi organizationManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of phagocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Protein transportIEA:UniProtKB-KW
Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulumManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Endoplasmic reticulum-Golgi intermediate compartment membrane
Golgi apparatus membrane
Endoplasmic reticulum membrane
Golgi apparatus membrane
Endoplasmic reticulum membrane
Topology
Lumenal: 45-322
Helical: 323-345
Cytoplasmic: 346-356
Helical: 323-345
Cytoplasmic: 346-356
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Anti-LMAN2 antibodies
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Target: LMAN2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-2926
Application*: E, WB
Target: LMAN2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYCL-365
Application*: WB
Target: LMAN2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1809
Application*: WB
Target: LMAN2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 264C4a
Application*: DB, WB
Target: LMAN2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-1808
Application*: E, IP, WB
Target: LMAN2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1807
Application*: EC
Target: LMAN2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-1806
Application*: WB, E, ED, IP
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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