LMAN2

This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus and the plasma membrane.
Full Name
LECTIN, MANNOSE BINDING 2
Function
Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans (By similarity).
Biological Process
Endoplasmic reticulum organizationManual Assertion Based On ExperimentIBA:GO_Central
Endoplasmic reticulum to Golgi vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Golgi organizationManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of phagocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Protein transportIEA:UniProtKB-KW
Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulumManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Endoplasmic reticulum-Golgi intermediate compartment membrane
Golgi apparatus membrane
Endoplasmic reticulum membrane
Topology
Lumenal: 45-322
Helical: 323-345
Cytoplasmic: 346-356
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Anti-LMAN2 antibodies

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Target: LMAN2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-2926
Application*: E, WB
Target: LMAN2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYCL-365
Application*: WB
Target: LMAN2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1809
Application*: WB
Target: LMAN2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 264C4a
Application*: DB, WB
Target: LMAN2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-1808
Application*: E, IP, WB
Target: LMAN2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1807
Application*: EC
Target: LMAN2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-1806
Application*: WB, E, ED, IP
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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