LRIG3
LRIG3 may play a role in craniofacial and inner ear morphogenesis during embryonic development. LRIG3 may act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1.
Full Name
leucine-rich repeats and immunoglobulin-like domains 3
Function
May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1 (By similarity).
Biological Process
Otolith morphogenesisIEA:Ensembl
Cellular Location
Cell membrane
Cytoplasmic vesicle membrane
Detected in cytoplasmic vesicles when coexpressed with ERBB4.
Cytoplasmic vesicle membrane
Detected in cytoplasmic vesicles when coexpressed with ERBB4.
Topology
Helical: 810-830
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Anti-LRIG3 antibodies
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Target: LRIG3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYCL-456
Application*: E, WB
Target: LRIG3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-1957
Application*: F
Target: LRIG3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4D5
Application*: E, WB
Target: LRIG3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1956
Application*: IH, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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