LRRC4

LRRC4 is significantly downregulated in primary brain tumors. The exact function of the protein encoded by this gene is unknown.
Full Name
leucine rich repeat containing 4
Function
Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays an important role for auditory synaptic responses. Involved in the suppression of glioma (By similarity).
Biological Process
Excitatory synapse assemblyManual Assertion Based On ExperimentIBA:GO_Central
Modulation of chemical synaptic transmissionManual Assertion Based On ExperimentIBA:GO_Central
Postsynaptic density protein 95 clusteringManual Assertion Based On ExperimentIBA:GO_Central
Synaptic membrane adhesionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Cell junction, synapse, postsynaptic cell membrane
LRRC4 and DLG4 are interdependent for synaptic localization.
Topology
Extracellular: 39-527
Helical: 528-548
Cytoplasmic: 549-653
PTM
N-glycosylated.
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Anti-LRRC4 antibodies

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Mouse Anti-LRRC4 Recombinant Antibody (CBYJL-2013) (CBMAB-L2118-YJ)

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Target: LRRC4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: CBYJL-2013
Application*: WB
Datasheet SDS

Mouse Anti-LRRC4 Recombinant Antibody (CBYJL-2012) (CBMAB-L2117-YJ)

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Target: LRRC4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-2012
Application*: IH
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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