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MAML3

MAML3 (Mastermind Like Transcriptional Coactivator 3) is a Protein Coding gene. Among its related pathways are Signaling by NOTCH1 and PI3K-Akt signaling pathway. Gene Ontology (GO) annotations related to this gene include transcription coactivator activity. An important paralog of this gene is MAML1.

Full Name

MASTERMIND LIKE TRANSCRIPTIONAL COACTIVATOR 3

Function

Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1.

Biological Process

Notch signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of transcription of Notch receptor targetManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus speckle
Nuclear, in a punctate manner.

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Anti-MAML3 antibodies

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Mouse Anti-MAML3 Recombinant Antibody (CBFYM-1356) (CBMAB-M1515-FY)

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Target: MAML3

Host: Mouse

Specificity: Human

Clone: CBFYM-1356

Application*: WB

Mouse Anti-MAML3 Recombinant Antibody (CBFYM-1355) (CBMAB-M1514-FY)

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Target: MAML3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYM-1355

Application*: DB

Mouse Anti-MAML3 Recombinant Antibody (MAML3/1303) (CBMAB-M0431-FY)

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Target: MAML3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: MAML3/1303

Application*: F, P, IF

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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