MAML3

MAML3 (Mastermind Like Transcriptional Coactivator 3) is a Protein Coding gene. Among its related pathways are Signaling by NOTCH1 and PI3K-Akt signaling pathway. Gene Ontology (GO) annotations related to this gene include transcription coactivator activity. An important paralog of this gene is MAML1.

Full Name

MASTERMIND LIKE TRANSCRIPTIONAL COACTIVATOR 3

Function

Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1.

Biological Process

Notch signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of transcription of Notch receptor targetManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus speckle
Nuclear, in a punctate manner.

Anti-MAML3 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-MAML3 Recombinant Antibody (CBFYM-1356) (CBMAB-M1515-FY)

Datasheet

SDS

Target: MAML3

Host: Mouse

Specificity: Human

Clone: CBFYM-1356

Application*: WB

Mouse Anti-MAML3 Recombinant Antibody (CBFYM-1355) (CBMAB-M1514-FY)

Datasheet

SDS

Target: MAML3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYM-1355

Application*: DB

Mouse Anti-MAML3 Recombinant Antibody (MAML3/1303) (CBMAB-M0431-FY)

Datasheet

SDS

Target: MAML3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: MAML3/1303

Application*: F, P, IF

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)