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MEX3B

This gene encodes an RNA-binding phosphoprotein that is part of the MEX3 (muscle excess 3) family of translational regulators. The encoded protein contains N-terminal nuclear export and nuclear localization signals and is exported from the cytoplasm to the nucleus. The protein binds to RNA via two KH domains and also colocalizes with MEX3A, Dcp1A decapping factor and Argonaute proteins within P (processing) bodies.
Full Name
MEX-3 RNA BINDING FAMILY MEMBER B
Function
RNA-binding protein. May be involved in post-transcriptional regulatory mechanisms.
Biological Process
Protein autophosphorylation Source: UniProtKB
Protein phosphorylation Source: UniProtKB
Cellular Location
Cytoplasm
Nucleus
Other locations
P-body
Cytoplasmic granule
Note: Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. Localization to P-bodies is dependent on 14-3-3.
PTM
Phosphorylation at Ser-462 creates a docking site for 14-3-3, which stabilizes the protein and modulates its ability to bind RNA.
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Anti-MEX3B antibodies

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Mouse Anti-MEX3B Recombinant Antibody (4C4) (CBMAB-A7617-LY)

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Target: MEX3B
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4C4
Application*: WB, E
Datasheet SDS

Mouse Anti-MEX3B (AA 60-159) Recombinant Antibody (CBFYM-2134) (CBMAB-M2316-FY)

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Target: MEX3B
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYM-2134
Application*: E, WB
Datasheet SDS

Mouse Anti-MEX3B Recombinant Antibody (CBCNR-536) (CBMAB-R0583-CN)

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Target: MEX3B
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBCNR-536
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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