MSC

The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq]
Full Name
musculin (activated B-cell factor-1)
Function
Transcription repressor capable of inhibiting the transactivation capability of TCF3/E47. May play a role in regulating antigen-dependent B-cell differentiation.
Biological Process
Branchiomeric skeletal muscle development Source: Ensembl
Cardiac conduction system development Source: BHF-UCL
Cellular response to leukemia inhibitory factor Source: Ensembl
Developmental process Source: GO_Central
Diaphragm development Source: Ensembl
Regulation of transcription, DNA-templated Source: GO_Central
Regulation of transcription by RNA polymerase II Source: GO_Central
Roof of mouth development Source: Ensembl
Skeletal muscle tissue development Source: GO_Central
Cellular Location
Nucleus
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Anti-MSC antibodies

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Mouse Anti-MSC Recombinant Antibody (4D7) (CBMAB-A5602-LY)

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Target: MSC
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4D7
Application*: WB, E
Datasheet SDS

Mouse Anti-MSC Recombinant Antibody (1D1) (CBMAB-A5601-LY)

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Target: MSC
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1D1
Application*: WB, E
Datasheet SDS

Mouse Anti-MSC Recombinant Antibody (CBFYM-2617) (CBMAB-M2805-FY)

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Target: MSC
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-2617
Application*: F
Datasheet SDS

Mouse Anti-MSC (AA 1-100) Recombinant Antibody (CBFYM-2616) (CBMAB-M2804-FY)

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Target: MSC
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYM-2616
Application*: E, WB
Datasheet SDS

Mouse Anti-MSC (AA 103-188) Recombinant Antibody (CBFYM-2615) (CBMAB-M2803-FY)

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Target: MSC
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-2615
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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