MUC13

Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues.

Full Name

MUCIN 13, CELL SURFACE ASSOCIATED

Function

Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.

Biological Process

Maintenance of gastrointestinal epithelium Source: UniProtKB

Cellular Location

Secreted
Plasma membrane
Cell membrane
Apical cell membrane
Note: Also exists as a soluble form.

Topology

Extracellular: 19-421
Helical: 422-442
Cytoplasmic: 443-512

PTM

Cleaved into two subunits, alpha and beta, probably between the first EGF domain and the SEA domain. Beta subunit contains the cytoplasmic tail and alpha subunit the extracellular tail. The homooligomerization into dimers is dependent on intrachain disulfide bonds.
Highly N-glycosylated.

Anti-MUC13 antibodies

Mouse Anti-MUC13 Recombinant Antibody (CBFYM-2792) (CBMAB-M2985-FY)

Datasheet

SDS

Target: MUC13

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYM-2792

Application*: F

Human Anti-MUC13 Recombinant Antibody (CBFYM-0398) (CBMAB-M0502-FY)

Datasheet

SDS

Target: MUC13

Host: Human

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYM-0398

Application*: F

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)