MUC13
Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues.
Full Name
MUCIN 13, CELL SURFACE ASSOCIATED
Function
Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.
Biological Process
Maintenance of gastrointestinal epithelium Source: UniProtKB
Cellular Location
Secreted
Plasma membrane
Cell membrane
Apical cell membrane
Note: Also exists as a soluble form.
Plasma membrane
Cell membrane
Apical cell membrane
Note: Also exists as a soluble form.
Topology
Extracellular: 19-421
Helical: 422-442
Cytoplasmic: 443-512
Helical: 422-442
Cytoplasmic: 443-512
PTM
Cleaved into two subunits, alpha and beta, probably between the first EGF domain and the SEA domain. Beta subunit contains the cytoplasmic tail and alpha subunit the extracellular tail. The homooligomerization into dimers is dependent on intrachain disulfide bonds.
Highly N-glycosylated.
Highly N-glycosylated.
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Anti-MUC13 antibodies
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Target: MUC13
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-2792
Application*: F
Target: MUC13
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0398
Application*: F
Target: MUC13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBT2477
Application*: WB, IH, F
Target: MUC13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBT4397
Application*: WB, IH, F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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