MUM1
MUM1 (Melanoma Associated Antigen (Mutated) 1) is a Protein Coding gene. Diseases associated with MUM1 include Melanoma. Among its related pathways are DNA Damage. Gene Ontology (GO) annotations related to this gene include nucleosome binding. An important paralog of this gene is MUM1L1.
Full Name
Melanoma Associated Antigen (Mutated) 1
Function
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Biological Process
Chromatin organization Source: UniProtKB
DNA repair Source: UniProtKB
DNA repair Source: UniProtKB
Cellular Location
Nucleus
Note: Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.
Note: Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.
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Anti-MUM1 antibodies
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Target: MUM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: A1257
Application*: ELISA, WB
Target: MUM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4G10
Application*: WB, IHC
Target: MUM1
Host: Mouse
Specificity: Human
Clone: IHC627
Application*: IH
Target: MUM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4664
Application*: IH
Target: MUM1
Host: Rabbit
Antibody Isotype: IgG1
Specificity: Human
Clone: MRQ-43
Application*: ELISA
Target: MUM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYR-0033
Application*: ELISA
Target: MUM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-2826
Application*: WB, IH, P
Target: MUM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-2825
Application*: E, IH, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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