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MUM1

MUM1 (Melanoma Associated Antigen (Mutated) 1) is a Protein Coding gene. Diseases associated with MUM1 include Melanoma. Among its related pathways are DNA Damage. Gene Ontology (GO) annotations related to this gene include nucleosome binding. An important paralog of this gene is MUM1L1.
Full Name
Melanoma Associated Antigen (Mutated) 1
Function
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Biological Process
Chromatin organization Source: UniProtKB
DNA repair Source: UniProtKB
Cellular Location
Nucleus
Note: Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.

Anti-MUM1 antibodies

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Rabbit Anti-MUM1 Monoclonal Antibody (MRQ-43) (CBMAB-R0055-FY)

Datasheet SDS
Target: MUM1
Host: Rabbit
Antibody Isotype: IgG1
Specificity: Human
Clone: MRQ-43
Application*: ELISA

Rabbit Anti-MUM1 Monoclonal Antibody (CBFYR-0033) (CBMAB-R0054-FY)

Datasheet SDS
Target: MUM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYR-0033
Application*: ELISA

Rabbit Anti-MUM1 (C-terminus) Recombinant Antibody (CBFYM-2826) (CBMAB-M3019-FY)

Datasheet SDS
Target: MUM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-2826
Application*: WB, IH, P

Mouse Anti-MUM1 Recombinant Antibody (CBFYM-2825) (CBMAB-M3018-FY)

Datasheet SDS
Target: MUM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-2825
Application*: E, IH, WB

Mouse Anti-MUM1 Recombinant Antibody (IHC627) (CBMAB-MA177-YC)

Datasheet SDS
Target: MUM1
Host: Mouse
Specificity: Human
Clone: IHC627
Application*: IH

Mouse Anti-MUM1 Recombinant Antibody (A1257) (CBMAB-AP12297LY)

Datasheet SDS
Target: MUM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: A1257
Application*: ELISA, WB

Mouse Anti-MUM1 Recombinant Antibody (4G10) (CBMAB-AO757LY)

Datasheet SDS
Target: MUM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4G10
Application*: WB, IHC
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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