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Mouse Anti-MUM1 Recombinant Antibody (4G10) (CBMAB-AO757LY)

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Summary

Host Animal
Mouse
Specificity
Human
Clone
4G10
Antibody Isotype
IgG1
Application
WB, IHC

Basic Information

Immunogen
Purified recombinant fragment of human MUM1 expressed in E. coli.
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Ascites
Preservative
0.03% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Melanoma Associated Antigen (Mutated) 1
Introduction
MUM1 (Melanoma Associated Antigen (Mutated) 1) is a Protein Coding gene. Diseases associated with MUM1 include Melanoma. Among its related pathways are DNA Damage. Gene Ontology (GO) annotations related to this gene include nucleosome binding. An important paralog of this gene is MUM1L1.
Entrez Gene ID
UniProt ID
Alternative Names
MUM-1; EXPAND1; HSPC211; FLJ14868; FLJ22283; MGC131891; MGC163315; MUM1; PWWP domain-containing protein MUM1; Mutated melanoma-associated antigen 1; MUM-1; Protein expandere EXPAND1; MUM1
Function
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Biological Process
Chromatin organization Source: UniProtKB
DNA repair Source: UniProtKB
Cellular Location
Nucleus
Note: Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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