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Mouse Anti-MUM1 Recombinant Antibody (A1257) (CBMAB-AP12297LY)

The product is antibody recognizes MUM1. The antibody A1257 immunoassay techniques such as: ELISA, WB.
See all MUM1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
A1257
Antibody Isotype
IgG2a
Application
ELISA, WB

Basic Information

Immunogen
Fusion Protein of MUM1
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
Affinity purity
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Melanoma Associated Antigen (Mutated) 1
Introduction
MUM1 (Melanoma Associated Antigen (Mutated) 1) is a Protein Coding gene. Diseases associated with MUM1 include Melanoma. Among its related pathways are DNA Damage. Gene Ontology (GO) annotations related to this gene include nucleosome binding. An important paralog of this gene is MUM1L1.
Entrez Gene ID
84939
UniProt ID
Q2TAK8
Alternative Names
Melanoma Associated Antigen (Mutated) 1; Mutated Melanoma-Associated Antigen 1; Protein Expandere; EXPAND1; MUM-1; PWWP Domain-Containing Protein MUM1; Melanoma Ubiquitous Mutated Protein; HSPC211;
Function
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Biological Process
Chromatin organization Source: UniProtKB
DNA repair Source: UniProtKB
Cellular Location
Nucleus
Note: Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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