MYBL2

The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined. [provided by RefSeq]
Full Name
v-myb myeloblastosis viral oncogene homolog (avian)-like 2
Function
Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene.
Biological Process
Cellular response to leukemia inhibitory factor Source: Ensembl
Mitotic cell cycle Source: GO_Central
Mitotic spindle assembly Source: Ensembl
Positive regulation of neuron apoptotic process Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of transcription, DNA-templated Source: GO_Central
Cellular Location
Nucleus
PTM
Phosphorylated by cyclin A/CDK2 during S-phase. Phosphorylation at Thr-520 is probably involved in transcriptional activity.
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Anti-MYBL2 antibodies

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Mouse Anti-MYBL2 Recombinant Antibody (1C7) (CBMAB-A5705-LY)

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Target: MYBL2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1C7
Application*: WB, E
Datasheet SDS

Mouse Anti-MYBL2 Recombinant Antibody (CBFYM-2873) (CBMAB-M3067-FY)

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Target: MYBL2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBFYM-2873
Application*: E, IC, WB
Datasheet SDS

Mouse Anti-MYBL2 Recombinant Antibody (CBFYM-2872) (CBMAB-M3066-FY)

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Target: MYBL2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-2872
Application*: ELISA, WB
Datasheet SDS

Mouse Anti-MYBL2 (AA 601-700) Recombinant Antibody (CBFYM-2871) (CBMAB-M3065-FY)

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Target: MYBL2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-2871
Application*: IF, WB
Datasheet SDS

Rabbit Anti-MYBL2 (AA 1-538) Recombinant Antibody (CBYY-1140) (CBMAB-1144-YY)

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Target: MYBL2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBYY-1140
Application*: WB, IP, P, F, CI, IC
Datasheet SDS

Human MYBL2 ELISA Kit (V2LY-0626-LY4914)

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Target: MYBL2
Sensitivity: 0.0091 ng/mL
Detection Range: 0.02-4.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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