MYBPC2

This gene encodes a member of the myosin-binding protein C family. This family includes the fast-, slow-and cardiac-type isoforms, each of which is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The protein encoded by this locus is referred to as the fast-type isoform. Mutations in the related but distinct genes encoding the slow-type and cardiac-type isoforms have been associated with distal arthrogryposis, type 1 and hypertrophic cardiomyopathy, respectively.

MYOSIN BINDING PROTEIN C, FAST TYPE

Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.

Cell adhesion Source: UniProtKB-KW
Muscle contraction Source: Ensembl

Cytosol
Other locations
Myosin filament