NCALD
This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Full Name
Neurocalcin Delta
Function
May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions.
Biological Process
Calcium-mediated signaling Source: GO_Central
Regulation of systemic arterial blood pressure Source: Ensembl
Vesicle-mediated transport Source: UniProtKB
Regulation of systemic arterial blood pressure Source: Ensembl
Vesicle-mediated transport Source: UniProtKB
Cellular Location
Cytosol
Golgi apparatus
clathrin coat of trans-Golgi network vesicle
Golgi apparatus
clathrin coat of trans-Golgi network vesicle
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Anti-NCALD antibodies
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Target: NCALD
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: A1298
Application*: ELISA, IHC, WB
Target: NCALD
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CF303
Application*: ELISA, WB, IHC
Target: NCALD
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 6B4E10
Application*: E, WB, IH
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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