NENF

This gene encodes a neurotrophic factor that may play a role in neuron differentiation and development. A pseudogene of this gene is found on chromosome 12. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2009]
Full Name
Neudesin Neurotrophic Factor
Function
Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival (PubMed:31536960).

Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes (By similarity).

Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways (By similarity).

Neurotrophic activity is enhanced by binding to heme (By similarity).

Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity).
Biological Process
Negative regulation of appetite Source: UniProtKB
Negative regulation of neuron death Source: UniProtKB
Positive regulation of MAPK cascade Source: Ensembl
Cellular Location
Mitochondrion
Endoplasmic reticulum
Extracellular region or secreted
extracellular space
Note: Localized to mitochondria and endoplasmic reticulum by PINK1 and PARK7.
View more

Anti-NENF antibodies

+ Filters
Loading...

Mouse Anti-NENF Recombinant Antibody (A1320) (CBMAB-AP12545LY)

Go to compareCompare
Target: NENF
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: A1320
Application*: ELISA, IF, IHC, WB
Datasheet SDS

Mouse Anti-NENF Recombinant Antibody (7D10) (CBMAB-N1970-WJ)

Go to compareCompare
Target: NENF
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 7D10
Application*: E, WB
Datasheet SDS

Mouse Anti-NENF Recombinant Antibody (4G9E12) (CBMAB-N1969-WJ)

Go to compareCompare
Target: NENF
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: 4G9E12
Application*: E, WB, IH, IF
Datasheet SDS

Mouse Anti-NENF Recombinant Antibody (CBWJN-1329) (CBMAB-N1968-WJ)

Go to compareCompare
Target: NENF
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJN-1329
Application*: WB, IH
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry