Mouse Nenf ELISA Kit (V2LY-0626-LY2741)

Name: Mouse Nenf ELISA Kit
SKU: V2LY-0626-LY2741
Rating: 5 (1 reviews)

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Tested Data

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity

0.00053 ng/mL

Detection Range

0.001-0.4 ng/mL

Sample Type

Serum, Plasma, cell culture supernates

Specificity

Mouse

Assay Type

Sandwich

Reactivity

Mouse

Assay Time

1.5 h

Molecule Mass

18.9 kDa

Components

Pre-coated ELISA Plate: 12 wells * 8 detachable strips
Standard solution: 0.5ml x1
Standard diluent: 3ml x1
Streptavidin-HRP: 6ml x1
Stop solution: 6ml x1
Substrate solution A: 6ml x1
Substrate solution B: 6ml x1
Wash buffer concentrate (25x): 20ml x1
Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 2-8°C

More Infomation

Target

Full Name

Neudesin Neurotrophic Factor

Function

Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival (PubMed:31536960).

Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes (By similarity).

Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways (By similarity).

Neurotrophic activity is enhanced by binding to heme (By similarity).

Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity).

Biological Process

Negative regulation of appetite Source: UniProtKB
Negative regulation of neuron death Source: UniProtKB
Positive regulation of MAPK cascade Source: Ensembl

Cellular Location

Mitochondrion
Endoplasmic reticulum
Extracellular region or secreted
extracellular space
Note: Localized to mitochondria and endoplasmic reticulum by PINK1 and PARK7.

Kamińska, J., Koper-Lenkiewicz, O. M., Ponikwicka-Tyszko, D., Lebiedzińska, W., Palak, E., Sztachelska, M., ... & Dymicka-Piekarska, V. (2023). New Insights on the Progesterone (P4) and PGRMC1/NENF Complex Interactions in Colorectal Cancer Progression. Cancers, 15(20), 5074.

Li, A., Su, X., Wang, Y., Cheng, G., Zan, L., & Wang, H. (2020). Effect of neudesin neurotrophic factor on differentiation of bovine preadipocytes and myoblasts in a co-culture system. Animals, 11(1), 34.

Su, X., Wang, Y., Li, A., Zan, L., & Wang, H. (2019). Neudesin neurotrophic factor promotes bovine preadipocyte differentiation and inhibits myoblast myogenesis. Animals, 9(12), 1109.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human NENF ELISA Kit (CAT#: V2LY-0626-LY4122)

Related Products

Human NENF ELISA Kit (CAT#: V2LY-0626-LY4122)

Mouse Anti-NENF Recombinant Antibody (4G9E12) (CAT#: CBMAB-N1969-WJ)

Mouse Anti-NENF Recombinant Antibody (CBWJN-1329) (CAT#: CBMAB-N1968-WJ)

Mouse Anti-NENF Recombinant Antibody (7D10) (CAT#: CBMAB-N1970-WJ)

Mouse Anti-NENF Recombinant Antibody (A1320) (CAT#: CBMAB-AP12545LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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