NID2

Basement membranes, which are composed of type IV collagens (see MIM 120130), laminins (see LAMC1; MIM 150290), perlecan (HSPG2; MIM 142461), and nidogen (see NID1; MIM 131390), are thin pericellular protein matrices that control a large number of cellular activities, including adhesion, migration, differentiation, gene expression, and apoptosis.[supplied by OMIM
Full Name
nidogen 2 (osteonidogen)
Function
Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions.
Biological Process
Basement membrane organizationManual Assertion Based On ExperimentTAS:BHF-UCL
Cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Cell-matrix adhesionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted, extracellular space, extracellular matrix, basement membrane
PTM
Highly N- and O-glycosylated.
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Anti-NID2 antibodies

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Rat Anti-NID2 Recombinant Antibody (JF6) (CBMAB-N2456-WJ)

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Target: NID2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: JF6
Application*: WB, E, FN
Datasheet SDS

Mouse Anti-NID2 Recombinant Antibody (4G8) (CBMAB-N2454-WJ)

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Target: NID2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4G8
Application*: E, WB
Datasheet SDS

Rat Anti-NID2 Recombinant Antibody (CBWJN-1405) (CBMAB-N2453-WJ)

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Target: NID2
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBWJN-1405
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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