OGN

This gene encodes a protein which induces ectopic bone formation in conjunction with transforming growth factor beta. This protein is a small proteoglycan which contains tandem leucine-rich repeats (LRR). Alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq]
Full Name
osteoglycin
Function
Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
Biological Process
Negative regulation of smooth muscle cell proliferationISS:UniProtKB
Cellular Location
Secreted, extracellular space, extracellular matrix
PTM
N- and O-glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
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Anti-OGN antibodies

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Target: OGN
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-3038
Application*: E
Target: OGN
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYM-3037
Application*: WB
Target: OGN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig
Clone: CBXO-0406
Application*: E, IH, WB
Target: OGN
Host: Mouse
Specificity: Human
Clone: CBXO-0042
Application*: WB, IC, P, C, E
Target: OGN
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXO-0153
Application*: WB
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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