OGN

This gene encodes a protein which induces ectopic bone formation in conjunction with transforming growth factor beta. This protein is a small proteoglycan which contains tandem leucine-rich repeats (LRR). Alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq]

Full Name

osteoglycin

Function

Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.

Biological Process

Negative regulation of smooth muscle cell proliferationISS:UniProtKB

Cellular Location

Secreted, extracellular space, extracellular matrix

PTM

N- and O-glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.

Anti-OGN antibodies

Mouse Anti-OGN (AA 200-298) Recombinant Antibody (CBFYM-3038) (CBMAB-M3234-FY)

Datasheet

SDS

Target: OGN

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYM-3038

Application*: E

Rat Anti-OGN (AA 20-298) Recombinant Antibody (CBFYM-3037) (CBMAB-M3233-FY)

Datasheet

SDS

Target: OGN

Host: Rat

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBFYM-3037

Application*: WB

Mouse Anti-OGN Recombinant Antibody (CBXO-0406) (CBMAB-O0646-CQ)

Datasheet

SDS

Target: OGN

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Pig

Clone: CBXO-0406

Application*: E, IH, WB

Mouse Anti-OGN Recombinant Antibody (CBXO-0042) (CBMAB-O0343-CQ)

Datasheet

SDS

Target: OGN

Host: Mouse

Specificity: Human

Clone: CBXO-0042

Application*: WB, IC, P, C, E

Rabbit Anti-OGN Recombinant Antibody (CBXO-0153) (CBMAB-O0342-CQ)

Datasheet

SDS

Target: OGN

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBXO-0153

Application*: WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)