OGN
This gene encodes a protein which induces ectopic bone formation in conjunction with transforming growth factor beta. This protein is a small proteoglycan which contains tandem leucine-rich repeats (LRR). Alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq]
Full Name
osteoglycin
Function
Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
Biological Process
Negative regulation of smooth muscle cell proliferationISS:UniProtKB
Cellular Location
Secreted, extracellular space, extracellular matrix
PTM
N- and O-glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
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Anti-OGN antibodies
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Target: OGN
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-3038
Application*: E
Target: OGN
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYM-3037
Application*: WB
Target: OGN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig
Clone: CBXO-0406
Application*: E, IH, WB
Target: OGN
Host: Mouse
Specificity: Human
Clone: CBXO-0042
Application*: WB, IC, P, C, E
Target: OGN
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXO-0153
Application*: WB
Target: OGN
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-298
Tag: His Tag
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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