OSBPL7
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding the same isoform have been identified. [provided by RefSeq]
Full Name
oxysterol binding protein-like 7
Biological Process
Bile acid biosynthetic processTAS:Reactome
Cellular response to cholesterolManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of proteasomal protein catabolic processManual Assertion Based On ExperimentIMP:BHF-UCL
Regulation of autophagy1 PublicationNAS:ParkinsonsUK-UCL
Cellular response to cholesterolManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of proteasomal protein catabolic processManual Assertion Based On ExperimentIMP:BHF-UCL
Regulation of autophagy1 PublicationNAS:ParkinsonsUK-UCL
Cellular Location
Cytoplasm, cytosol
Endoplasmic reticulum membrane
Cell membrane
Endoplasmic reticulum membrane
Cell membrane
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Anti-OSBPL7 antibodies
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Target: OSBPL7
Host: Mouse
Specificity: Human
Clone: CBXO-0334
Application*: WB, IP, IF, E
Target: OSBPL7
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3D11
Application*: E, WB
Target: OSBPL7
Sensitivity: 0.092 ng/mL
Detection Range: 0.2-60 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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