PCOLCE

Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino-and carboxyl-terminal peptide extensions known as N-and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity.
Full Name
Procollagen C-Endopeptidase Enhancer
Function
Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity.
C-terminal processed part of PCPE (CT-PCPE) may have an metalloproteinase inhibitory activity.
Biological Process
Multicellular organism developmentManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted
PTM
C-terminally processed at multiple positions.
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Anti-PCOLCE antibodies

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Target: PCOLCE
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYC-P223
Application*: E, IC, WB
Target: PCOLCE
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: 261730
Application*: IP, WB
Target: PCOLCE
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 18
Application*: E
Target: PCOLCE
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: 14L782
Application*: WB
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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