PCYOX1
Prenylcysteine is released during the degradation of prenylated proteins. PCYOX1 catalyzes the degradation of prenylcysteine to yield free cysteines and a hydrophobic isoprenoid product (Tschantz et al., 1999 [PubMed 10585463]).[supplied by OMIM
Full Name
prenylcysteine oxidase 1
Function
Prenylcysteine oxidase that cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (PubMed:10585463, PubMed:11078725, PubMed:12186880).
Only active against free prenylcysteines and not prenylcysteine residues within prenylated proteins or peptides (By similarity).
Involved in the final step in the degradation of prenylated proteins, by degrading prenylcysteines after the protein has been degraded (PubMed:10585463).
Only active against free prenylcysteines and not prenylcysteine residues within prenylated proteins or peptides (By similarity).
Involved in the final step in the degradation of prenylated proteins, by degrading prenylcysteines after the protein has been degraded (PubMed:10585463).
Biological Process
Chloride transmembrane transportIEA:Ensembl
Prenylated protein catabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Prenylcysteine catabolic processIEA:Ensembl
Prenylated protein catabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Prenylcysteine catabolic processIEA:Ensembl
Cellular Location
Lysosome
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Anti-PCYOX1 antibodies
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Target: PCYOX1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5E151
Application*: E
Target: PCYOX1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3D7-D8
Application*: E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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