POP7

POP7 (POP7 Homolog, Ribonuclease P/MRP Subunit) is a protein coding gene. Among its related pathways are RNA transport and tRNA processing. Gene Ontology annotations related to this gene include nucleic acid binding and ribonuclease P activity.

Full Name

processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)

Function

Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:9630247, PubMed:30454648).
Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465).

Biological Process

RNA phosphodiester bond hydrolysis, endonucleolyticManual Assertion Based On ExperimentIBA:GO_Central
rRNA processingIEA:UniProtKB-KW
tRNA 5'-leader removalManual Assertion Based On ExperimentIDA:UniProtKB
tRNA processingManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus, nucleolus
Cytoplasm
Cytoplasmic granule
Under stress conditions colocalizes with SMN1 in punctuated cytoplasmic granules.

Anti-POP7 antibodies

Mouse Anti-POP7 Recombinant Antibody (3F12) (CBMAB-P2408-YC)

Datasheet

SDS

Target: POP7

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 3F12

Application*: E

Mouse Anti-POP7 Recombinant Antibody (D-6) (CBMAB-R0653-CN)

Datasheet

SDS

Target: POP7

Host: Mouse

Specificity: Human

Clone: D-6

Application*: WB, IP, IF, E

Mouse Anti-POP7 Recombinant Antibody (5BH5) (CBMAB-R0652-CN)

Datasheet

SDS

Target: POP7

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 5BH5

Application*: E, WB

Mouse Anti-POP7 Recombinant Antibody (1F11) (CBMAB-R0651-CN)

Datasheet

SDS

Target: POP7

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 1F11

Application*: E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)