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Mouse Anti-POP7 Recombinant Antibody (3F12) (CBMAB-P2408-YC)

Provided herein is a Mouse monoclonal antibody against Human POP7 homolog, ribonuclease P/MRP subunit. The antibody can be used for immunoassay techniques, such as ELISA.
See all POP7 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3F12
Antibody Isotype
IgG1, κ
Application
ELISA

Basic Information

Immunogen
POP7 (NP_005828.1, 1-80 aa) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
Introduction
POP7 (POP7 Homolog, Ribonuclease P/MRP Subunit) is a protein coding gene. Among its related pathways are RNA transport and tRNA processing. Gene Ontology annotations related to this gene include nucleic acid binding and ribonuclease P activity.
Entrez Gene ID
10248
UniProt ID
O75817
Alternative Names
0610037N12Rik; RPP2; RPP20
Function
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:9630247, PubMed:30454648).
Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465).
Biological Process
RNA phosphodiester bond hydrolysis, endonucleolyticManual Assertion Based On ExperimentIBA:GO_Central
rRNA processingIEA:UniProtKB-KW
tRNA 5'-leader removalManual Assertion Based On ExperimentIDA:UniProtKB
tRNA processingManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus, nucleolus
Cytoplasm
Cytoplasmic granule
Under stress conditions colocalizes with SMN1 in punctuated cytoplasmic granules.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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