Mouse Anti-POP7 Recombinant Antibody (3F12) (CBMAB-P2408-YC)

Name: Mouse Anti-POP7 Recombinant Antibody (3F12)
SKU: CBMAB-P2408-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

3F12

Application

ELISA

Immunogen

POP7 (NP_005828.1, 1-80 aa) partial recombinant protein with GST tag.

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)

Introduction

POP7 (POP7 Homolog, Ribonuclease P/MRP Subunit) is a protein coding gene. Among its related pathways are RNA transport and tRNA processing. Gene Ontology annotations related to this gene include nucleic acid binding and ribonuclease P activity.

Entrez Gene ID

10248

UniProt ID

O75817

Alternative Names

0610037N12Rik; RPP2; RPP20

Function

Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:9630247, PubMed:30454648).
Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465).

Biological Process

RNA phosphodiester bond hydrolysis, endonucleolyticManual Assertion Based On ExperimentIBA:GO_Central
rRNA processingIEA:UniProtKB-KW
tRNA 5'-leader removalManual Assertion Based On ExperimentIDA:UniProtKB
tRNA processingManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus, nucleolus
Cytoplasm
Cytoplasmic granule
Under stress conditions colocalizes with SMN1 in punctuated cytoplasmic granules.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Mouse Anti-POP7 Recombinant Antibody (D-6) (CAT#: CBMAB-R0653-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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