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Mouse Anti-POP7 Recombinant Antibody (1F11) (CBMAB-R0651-CN)

This product is a Mouse antibody that recognizes POP7. The antibody 1F11 can be used for immunoassay techniques such as: ELISA.
See all POP7 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1F11
Antibody Isotype
IgG2a
Application
ELISA

Basic Information

Immunogen
Recombinant GST-human RPP20 (NCBI accession number aa. C24113, expression vector pGEC-2T), expressed in E.coli
Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
LYOPH
Buffer
10mM Ammonium bicarbonate buffer

Target

Full Name
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
Introduction
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP complex, which cleaves pre-rRNA sequences.
Entrez Gene ID
10248
UniProt ID
O75817
Alternative Names
RPP2; RPP20; 0610037N12Rik
Function
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:9630247, PubMed:30454648).
Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465).
Biological Process
RNA phosphodiester bond hydrolysis, endonucleolyticManual Assertion Based On ExperimentIBA:GO_Central
rRNA processingIEA:UniProtKB-KW
tRNA 5'-leader removalManual Assertion Based On ExperimentIDA:UniProtKB
tRNA processingManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus, nucleolus
Cytoplasm
Cytoplasmic granule
Under stress conditions colocalizes with SMN1 in punctuated cytoplasmic granules.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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