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Mouse Anti-POP7 Recombinant Antibody (1F11) (CBMAB-R0651-CN)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1F11
Antibody Isotype
IgG2a
Application
ELISA

Basic Information

Immunogen
Recombinant GST-human RPP20 (NCBI accession number aa. C24113, expression vector pGEC-2T), expressed in E.coli
Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
LYOPH
Buffer
10mM Ammonium bicarbonate buffer

Target

Full Name
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
Introduction
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP complex, which cleaves pre-rRNA sequences.
Entrez Gene ID
10248
UniProt ID
O75817
Alternative Names
RPP2; RPP20; 0610037N12Rik
Function
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:9630247, PubMed:30454648).
Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465).
Biological Process
RNA phosphodiester bond hydrolysis, endonucleolyticManual Assertion Based On ExperimentIBA:GO_Central
rRNA processingIEA:UniProtKB-KW
tRNA 5'-leader removalManual Assertion Based On ExperimentIDA:UniProtKB
tRNA processingManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus, nucleolus
Cytoplasm
Cytoplasmic granule
Under stress conditions colocalizes with SMN1 in punctuated cytoplasmic granules.
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For research use only. Not intended for any clinical use.

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