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PPP1R2

Protein phosphatase-1 (PP1) is one of the main eukaryotic serine/threonine phosphatases. The protein encoded by this gene binds to the catalytic subunit of PP1, strongly inhibiting its activity. Ten related pseudogenes have been found throughout the human genome.

Full Name

PPP1R2

Function

Inhibitor of protein-phosphatase 1.

Biological Process

Generation of precursor metabolites and energyManual Assertion Based On ExperimentTAS:ProtInc
Glycogen metabolic processIEA:UniProtKB-KW
Regulation of phosphoprotein phosphatase activityManual Assertion Based On ExperimentIBA:GO_Central
Regulation of signal transductionIEA:InterPro

PTM

Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex (By similarity).
Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex.

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Anti-PPP1R2 antibodies

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Mouse Anti-PPP1R2 Recombinant Antibody (2E9) (CBMAB-P2615-YC)

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Target: PPP1R2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2E9

Application*: E, P, WB

Mouse Anti-PPP1R2 Recombinant Antibody (2E9)

PPP1R2 Matched Antibody Pair (914) (APMAB-914LY)

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Target: PPP1R2

Specificity: Human

PPP1R2 Matched Antibody Pair (914)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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