loading...

PWP1

PWP1 contains several WD-40 repeats and is found mostly in the nucleus. The expression and localization of this protein are cell cycle dependent. Expression of this gene is upregulated in pancreatic adenocarcinoma.

Full Name

PWP1

Function

Chromatin-associated factor that regulates transcription (PubMed:29065309).
Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription (PubMed:29065309).
Regulates the epigenetic status of rDNA (PubMed:29065309).

Biological Process

Histone H4-K20 trimethylationIEA:Ensembl
Negative regulation of peptidyl-serine phosphorylation of STAT proteinIEA:Ensembl
Positive regulation of stem cell differentiationIEA:Ensembl
Positive regulation of transcription of nucleolar large rRNA by RNA polymerase IManual Assertion Based On ExperimentIDA:FlyBase
rRNA processingIEA:InterPro
Transcription, DNA-templatedManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Nucleus
Nucleus, nucleolus
Chromosome
Associates with chromatin regions of rDNA.

View more

Anti-PWP1 antibodies

+ Filters

Loading...

Mouse Anti-PWP1 Recombinant Antibody (3A11) (CBMAB-P3550-YC)

Compare

Target: PWP1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 3A11

Application*: E, IC, IF, WB

Mouse Anti-PWP1 Recombinant Antibody (2851C5a) (CBMAB-P3549-YC)

Compare

Target: PWP1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 2851C5a

Application*: DB

Mouse Anti-PWP1 Recombinant Antibody (1A12) (CBMAB-P3548-YC)

Compare

Target: PWP1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1A12

Application*: E, WB

PWP1 Matched Antibody Pair (948) (APMAB-948LY)

Compare

Target: PWP1

Specificity: Human

More Infomation

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

online inquiry

Online Inquiry