RABL6
This gene encodes a member of the Ras superfamily of small GTPases. The encoded protein binds to both GTP and GDP and may play a role in cell growth and survival. Overexpression of this gene may play a role in breast cancer tumorigenesis, and pseudogenes of this gene are located on the long arm of chromosome 2 and the short arm of chromosome 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Full Name
RAB, Member RAS Oncogene Family Like 6
Function
May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A.
Cellular Location
Isoform 1
Cytoplasm
Predominantly cytoplasmic (PubMed:17962191).
Isoform 3
Nucleus
Predominantly nuclear (PubMed:17962191).
Cytoplasm
Predominantly cytoplasmic (PubMed:17962191).
Isoform 3
Nucleus
Predominantly nuclear (PubMed:17962191).
PTM
Isoform 1 is O-glycosylated, while other isoforms are not.
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Anti-RABL6 antibodies
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Target: RABL6
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2E11-1F10
Application*: WB, E
Target: RABL6
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBLC257-LY
Application*: WB
Target: RABL6
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-0687
Application*: IF, SE, E, WB
Target: RABL6
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2E11-1F10
Application*: E, IF, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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