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Mouse Anti-RABL6 Recombinant Antibody (2E11-1F10) (CBMAB-R0987-CN)

This product is a Mouse antibody that recognizes RABL6. The antibody 2E11-1F10 can be used for immunoassay techniques such as: ELISA, IF, WB.
See all RABL6 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2E11-1F10
Antibody Isotype
IgG2a, κ
Application
ELISA, IF, WB

Basic Information

Immunogen
Full length recombinant corresponding to aa. 1-478 from human C9orf86 (H02945) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
RAB, Member RAS Oncogene Family Like 6
Introduction
This gene encodes a member of the Ras superfamily of small GTPases. The encoded protein binds to both GTP and GDP and may play a role in cell growth and survival. Overexpression of this gene may play a role in breast cancer tumorigenesis, and pseudogenes of this gene are located on the long arm of chromosome 2 and the short arm of chromosome 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Entrez Gene ID
55684
UniProt ID
Q3YEC7
Alternative Names
RAB, Member RAS Oncogene Family Like 6; Partner Of ARF; Rab-Like Protein 1; C9orf86; RBEL1; PARF; Chromosome 9 Open Reading Frame 86;
Function
May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A.
Cellular Location
Isoform 1
Cytoplasm
Predominantly cytoplasmic (PubMed:17962191).
Isoform 3
Nucleus
Predominantly nuclear (PubMed:17962191).
PTM
Isoform 1 is O-glycosylated, while other isoforms are not.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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